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Danny Rischin Selected Research

Tirapazamine (SR 4233)

1/2017Effect of p16 Status on the Quality-of-Life Experience During Chemoradiation for Locally Advanced Oropharyngeal Cancer: A Substudy of Randomized Trial Trans-Tasman Radiation Oncology Group (TROG) 02.02 (HeadSTART).
4/2016Quantitative and qualitative analysis of [(18)F]FDG and [(18)F]FAZA positron emission tomography of head and neck cancers and associations with HPV status and treatment outcome.
10/2015Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.
2/2014Correlation of p16 status, hypoxic imaging using [18F]-misonidazole positron emission tomography and outcome in patients with loco-regionally advanced head and neck cancer.
6/2013Treatment response in the neck: p16+ versus p16- oropharyngeal cancer.
3/2012Prognostic and predictive significance of plasma HGF and IL-8 in a phase III trial of chemoradiation with or without tirapazamine in locoregionally advanced head and neck cancer.
1/2012Prognostic significance of plasma osteopontin in patients with locoregionally advanced head and neck squamous cell carcinoma treated on TROG 02.02 phase III trial.
9/2010Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial.
7/2010Phase 1 study of tirapazamine in combination with radiation and weekly cisplatin in patients with locally advanced cervical cancer.
6/2010Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): a phase III trial of the Trans-Tasman Radiation Oncology Group.
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Danny Rischin Research Topics

Disease

48Neoplasms (Cancer)
01/2022 - 01/2002
35Squamous Cell Carcinoma of Head and Neck
01/2022 - 10/2004
22Head and Neck Neoplasms (Head and Neck Cancer)
05/2022 - 03/2004
19Squamous Cell Carcinoma (Epidermoid Carcinoma)
10/2021 - 03/2004
14Hypoxia (Hypoxemia)
01/2022 - 12/2004
12Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2013 - 01/2003
10Ovarian Neoplasms (Ovarian Cancer)
12/2019 - 06/2003
9Carcinoma (Carcinomatosis)
03/2020 - 06/2002
6Oropharyngeal Neoplasms
10/2022 - 09/2010
5Uterine Cervical Neoplasms (Cancer of the Cervix)
10/2022 - 07/2010
5Merkel Cell Carcinoma
06/2018 - 12/2003
4Neoplasm Metastasis (Metastasis)
11/2018 - 01/2003
3Disease Progression
10/2022 - 10/2010
3Pain (Aches)
01/2022 - 10/2009
3Infections
12/2020 - 08/2011
3Nasopharyngeal Carcinoma
05/2013 - 04/2002
3Febrile Neutropenia
05/2013 - 04/2002
2Nasopharyngeal Neoplasms (Cancer of the Nasopharynx)
01/2021 - 04/2002
2Body Weight (Weight, Body)
01/2021 - 01/2018
2Hemorrhage
10/2020 - 04/2009
2Melanoma (Melanoma, Malignant)
10/2020 - 12/2018
2Neutropenia
01/2019 - 07/2010
2Squamous Cell Neoplasms (Squamous Cell Cancer)
01/2017 - 09/2010
2Lung Neoplasms (Lung Cancer)
09/2012 - 10/2010
2Thyroid Neoplasms (Thyroid Cancer)
01/2012 - 06/2008
2Chronic Hepatitis B
08/2011 - 05/2011
2Margins of Excision
02/2010 - 12/2003
2Thrombosis (Thrombus)
10/2009 - 06/2002
2Unknown Primary Neoplasms
05/2005 - 02/2003
1Skin Neoplasms (Skin Cancer)
10/2022
1Adenocarcinoma
11/2020
1Tonsillar Neoplasms
03/2020
1Cognitive Dysfunction
01/2020
1Hearing Loss (Hearing Impairment)
01/2020
1Cranial Nerve Diseases (Cranial Nerve Disorders)
01/2020
1Anus Neoplasms (Anal Cancer)
02/2019
1Thrombocytopenia (Thrombopenia)
01/2019
1Drug-Related Side Effects and Adverse Reactions
01/2019
1Rheumatic Diseases (Rheumatism)
12/2018
1Mucositis
11/2018

Drug/Important Bio-Agent (IBA)

19Cisplatin (Platino)FDA LinkGeneric
11/2021 - 04/2002
14Tirapazamine (SR 4233)IBA
01/2017 - 01/2005
10PlatinumIBA
10/2022 - 05/2004
10Biomarkers (Surrogate Marker)IBA
01/2022 - 06/2011
10Fluorouracil (Carac)FDA LinkGeneric
11/2019 - 04/2002
10Carboplatin (JM8)FDA LinkGeneric
01/2019 - 06/2002
8cemiplimabIBA
10/2022 - 01/2018
7pembrolizumabIBA
01/2022 - 10/2018
6Cetuximab (Erbitux)FDA Link
01/2022 - 01/2016
5Immune Checkpoint InhibitorsIBA
01/2021 - 01/2018
5Cytotoxins (Cytolysins)IBA
01/2012 - 12/2004
5ErbB Receptors (EGF Receptor)IBA
06/2011 - 01/2002
4LigandsIBA
10/2022 - 01/2016
4Tyrosine Kinase InhibitorsIBA
01/2022 - 06/2003
4Fluorine-18IBA
06/2018 - 12/2004
4Cyclin-Dependent Kinase Inhibitor p16IBA
08/2012 - 06/2011
4Gefitinib (Iressa)FDA Link
04/2009 - 01/2002
3ProdrugsIBA
01/2022 - 03/2010
3Pharmaceutical PreparationsIBA
01/2019 - 01/2016
3GemcitabineFDA Link
01/2019 - 05/2013
3Proteins (Proteins, Gene)FDA Link
11/2013 - 06/2011
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2021 - 03/2016
2atezolizumabIBA
01/2020 - 10/2018
2BNC 105PIBA
01/2019 - 08/2011
2CyclinsIBA
04/2017 - 11/2013
2ParaffinIBA
01/2016 - 08/2012
2MisonidazoleIBA
02/2014 - 05/2006
2DNA (Deoxyribonucleic Acid)IBA
01/2014 - 04/2011
2Erlotinib Hydrochloride (CP 358,774)FDA Link
09/2012 - 10/2010
2InterleukinsIBA
03/2012 - 04/2011
2Sunitinib (Sutent)FDA Link
04/2011 - 06/2008
2Angiogenesis InhibitorsIBA
04/2011 - 10/2010
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2010 - 06/2008
2Etoposide (VP 16)FDA LinkGeneric
11/2008 - 12/2003
2fluoromisonidazoleIBA
05/2006 - 12/2005
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2021
1B7-H1 AntigenIBA
11/2020
1Messenger RNA (mRNA)IBA
11/2020
1talimogene laherparepvecIBA
10/2020
1Monoclonal AntibodiesIBA
01/2020
1Immunoglobulins (Immunoglobulin)IBA
01/2020
1Mitomycin (Mitomycin-C)FDA LinkGeneric
02/2019
1Oncogene Proteins (Oncogene Protein)IBA
10/2018
1durvalumabIBA
10/2018
1NivolumabIBA
10/2018
1Interferon-gamma (Interferon, gamma)IBA
10/2018

Therapy/Procedure

48Radiotherapy
05/2022 - 06/2002
27Therapeutics
10/2022 - 06/2003
25Drug Therapy (Chemotherapy)
10/2022 - 04/2002
16Chemoradiotherapy
11/2021 - 01/2003
4Immunotherapy
10/2021 - 10/2020
3Induction Chemotherapy
05/2013 - 04/2002
2Neck Dissection (Radical Neck Dissection)
01/2021 - 02/2010
2Conformal Radiotherapy
03/2020 - 01/2020
2Adjuvant Chemotherapy
08/2011 - 12/2003
1Terminal Care (Care, Terminal)
05/2021
1Palliative Care (Palliative Therapy)
05/2021
1Stem Cell Transplantation
12/2020
1Length of Stay
12/2020
1Combined Modality Therapy
06/2020